The plasma membrane is freely permeable to steroid hormones

In breast tissue, mammary epithelial cells express PMCA2, which transports calcium across the apical surface of the cells into milk. PMCA2 expression falls on weaning, leading to calcium-induced apoptosis and mammary gland involution. Persistent PMCA2 expression in certain breast cancers lowers calcium levels inside malignant cells, allowing them to avoid apoptosis. These tumors are also usually positive for the HER2 protein, tend to involve the lymph nodes, and are more common among young women, which could help explain their worse prognosis compared with postmenopausal women. [13]

The plasma membrane is freely permeable to steroid hormones

the plasma membrane is freely permeable to steroid hormones

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the plasma membrane is freely permeable to steroid hormonesthe plasma membrane is freely permeable to steroid hormonesthe plasma membrane is freely permeable to steroid hormonesthe plasma membrane is freely permeable to steroid hormonesthe plasma membrane is freely permeable to steroid hormones

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