Steroid abuse can also affect the heart (cardiovascular system) and cholesterol (lipid profile). Generally, in studies where steroids are abused, HDL-cholesterol (the good stuff) declines, and LDL-cholesterol tends to go up. Yeah, the good cholesterol goes down and the bad cholesterol goes up. In a related area, the heart often has to work harder because of this, and there also seems to be a steroid-related mild hypertrophy of the left ventricle which is accompanied by a decreased diastolic relaxation. This is very unclear, as regards steroid use, with regards to potential for reversibility and what portion is due to steroid use and what portion is due to training, which also increases ventricle size. Also in a related vein (ha ha) are increases in diastolic blood pressure. All of this increases risk for cardiovascular disease.
Acne is often present. Acne conglobata is a particularly severe form of acne that can develop during steroid abuse or even after the drug has been discontinued. Infections are a common side effect of steroid abuse because of needle sharing and unsanitary techniques used when injecting the drugs into the skin. These are similar risks to IV drug abusers with increased potential to acquire blood-borne infections such as hepatitis and HIV/AIDS . Skin abscesses may occur at injection sites and may spread to other organs of the body. Endocarditis or an infection of the heart valves is not uncommon.
Anabolic steroids can cause the development of acne. However, the extent to which it is experienced can be due to a number of varying factors, with the particular steroids and exact dosages used being primary. The skin´s sebaceous glands have a particularly high affinity to Dihydrotestosterone, which is an androgen the body naturally produces from testosterone via the enzyme 5-alpha Reductase. Increased sebaceous gland activity promotes oily skin which can combine with bacteria and dead skin (normal wear and tear) eventually causing pores to become clogged more quickly than the body can cleanse them. This of course, is preventable by using only particular steroids, cleansing the skin regularly, and perhaps using a topical anti-androgen.