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I am a dentist and a patient of the Professor Malone Lee mentioned in the article. I have suffered chronic UTI for five years and it is life ruining.
It started in my final year of dental school with an acute UTI. I had a few different courses of antibiotics and the symptoms eventually settled but didn't go away completely. I went back to my GP and asked for more antibiotics. I still had niggling low grade UTI symptoms and knew it hadn't fully gone away. Now my tests were coming back negative or as 'mixed growth of insignificance'. I became more and more unwell. I became fatigued and struggled to attend university. All the while my UTI symptoms remained. I went back to my GP and had bloods, they couldn't find anything wrong with me. I begged them for antibiotics till I was blue in the face. I knew I still had a UTI and it was making me very unwell.
Eventually I dropped out of dental school. I went to see urologists had all the scans and a cystoscopy, I saw ME specialists. No one could work it out. I was bed bound for a year. Eventually I was referred to Professor Malone Lee at the LUTS clinic at Whittington hospital in London. When I saw him my urine was saturated with white blood cells and epithelial cells. When he said you have a UTI I cried with happiness.
I have since been on oral antibiotics which control it, for some eradication takes 6 months, for others longer. Because the bacteria were left to live in my urine they learnt to invade the epithelial cells lining the bladder. Inside the cells they replicate hidden from wbc's and antibiotics. When the cell is shed the bacteria infect new cells. Long term antibiotics stop the reinfection of new cells. Eradication can, for some, take a long time. The long term antibiotics have given me my life back. New treatments are being developed.
Had my GP known that both dipsticks and MSU's are NOT reliable and in fact miss up to 50% of genuine infection maybe she would have given me a longer course of antibiotics in the first place and saved me a lot of misery.
MSU culture has been discredited in the literature as far back as 1983.
Partial treatment of UTI because of the reliance on these insensitive tests for diagnosis is causing serious chronic disease in an estimated % of the population.
I am part of a patient campaign Chronic Urinary Tract Infection campaign (CUTIC). We aim to raise awareness of the failings of currents testing regimes for UTI and to lobby for better guidelines for diagnosing and treating UTI.

The National Popular Vote bill seeks to effectively abolish the Electoral College by enacting state laws that give all electors from those states that have passed the bill to the winner of the national popular vote. Direct elections would become universal when enough state legislatures have passed legislation to make up a majority of the electoral vote (270 of 538). Eight states and the District of Columbus, totaling 132 electoral votes, have passed NPV laws. The Electoral College was created to ensure that less populous states would not be overlooked in presidential elections. If successful, this effort will make vast swaths of our nation completely irrelevant to presidential candidates, as they would then focus all their efforts on large population centers.

Couple three books of noteworthy info are:
“The Future of Nuclear Deterrence” (couldn’t find my copy to give author)
For a good sci-fi read with an appendix containing solid info for survival: “Pulling Through”, Dean Ing, Ace Science Fiction (home-made radiometers and air filtration)
“Coup de Etat” Edward Luttwak, Fawcett books. Gives solid info on just how hard it is to take over a nation. If you attack a nation, you absolutely must gain “command and control” of the nation within hours. You fail, you die. This was the strategy and tactics behind Bush’s “shock and awe” in Iraq.

30 mg/kg/dose (Max: 1 gram/dose) IV or IM once daily for 1 to 3 days. High-dose pulse steroids may be considered as an alternative to a second infusion of IVIG or for retreatment of patients who have had recurrent or recrudescent fever after additional IVIG, but should not be used as routine primary therapy with IVIG in patients with Kawasaki disease. Corticosteroid treatment has been shown to shorten the duration of fever in patients with IVIG-refractory Kawasaki disease or patients at high risk for IVIG-refractory disease. A reduction in the frequency and severity of coronary artery lesions has also been reported with pulse dose methylprednisolone treatment.

It’s therefore natural to think of antibiotic therapy as the natural opposite of steroids, and this has some truth to it. In the case of infection — which, remember, is not the only cause of inflammation — steroids do inhibit the immune response. But bear in mind that antibiotics do not, as a general rule, actually support or promote the body’s inflammatory response; rather, they work independently by attacking the infection directly along their own pathways. The result is that some pathologies (such as the contentious cases of sepsis and epiglottitis) may respond  both to steroids — to manage the excessive inflammatory response — and antibiotics — to help eliminate the source infection.

Iv pulse steroids

iv pulse steroids

30 mg/kg/dose (Max: 1 gram/dose) IV or IM once daily for 1 to 3 days. High-dose pulse steroids may be considered as an alternative to a second infusion of IVIG or for retreatment of patients who have had recurrent or recrudescent fever after additional IVIG, but should not be used as routine primary therapy with IVIG in patients with Kawasaki disease. Corticosteroid treatment has been shown to shorten the duration of fever in patients with IVIG-refractory Kawasaki disease or patients at high risk for IVIG-refractory disease. A reduction in the frequency and severity of coronary artery lesions has also been reported with pulse dose methylprednisolone treatment.

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